Capsaicin: When the "Chili" Is Too Hot (2024)

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Although many people enjoy the spicy heat that chili peppers and cayenne peppers add to food, heat seekers need to be aware of potential hazards.

The source of this flavor in peppers is known as capsaicin. Capsaicin is also found in topical medications used to treat disorders like pain and arthritis and in riot control agents and personal protective agents like pepper spray and pepper mace. This naturally occurring compound works on the body by stimulating pain fibers through the release of somatostatin.

Although usually enjoyable in our food, too much hot pepper can result in nausea, vomiting, abdominal pain, diarrhea and a burning sensation when ingested. During meal preparation, if capsaicin-containing oils get on the skin, it can lead to pain and redness with irritation. And if the pepper juices happen to inadvertently squirt into the eye, intense pain, tearing and redness can result. When inhaled, capsaicin can trigger an asthma attack or respiratory distress in susceptible people.

To help alleviate the burning sensation caused from eating capsaicin, small sips of milk or water may be helpful. If the eye has been affected, irrigation with copious warm water for 15 minutes is the first step. Using cool compresses may also provide relief. If the skin is exposed, warm water flushes, vegetable oil, diluted vinegar with water soaks and an antacid preparation (like Maalox®) applied to the skin may be helpful.

Also, removal from the source is critical. If the person is experiencing any trouble breathing or chest discomfort, call 911. For additional information or questions, call Poison Control at 1-800-222-1222.

Amanda McDaniel-Price, RN, BA, BSN
Certified Specialist in Poison Information

Poisoned?

Call 1-800-222-1222 or

HELP ME online

Prevention Tips

  • Wear rubber, latex, or nitrile gloves when working with hot peppers.
  • Open the windows or use fresh air if preparing or cooking hot peppers.
  • Do NOT touch face or eyes after preparing hot peppers.
  • If you choose to carry pepper spray, store and use it safely.

This Really Happened

Case 1: A young woman called Poison Control complaining of pain and blistering on her skin after handling hot chili peppers with bare hands an hour before. She had already tried washing with water, milk, and vinegar and had taken ibuprofen. Poison Control recommended applying a liquid antacid to the skin. However, the patient couldn't tolerate the pain and went to an emergency room. In the emergency room her hands were wrapped in gauze soaked in antibiotic ointment. She was given a narcotic pain reliever. The following day in a follow-up call from Poison Control the patient reported that her skin was somewhat improved but that her hands were still red, dry and cracked. She was using a moisturizing cream on the affected areas. Five days later she reported to Poison Control that she was much better.

Case 2: A teenage boy ate some food that had very hot chili peppers in it. He vomited and developed diarrhea and throat irritation. His mother called Poison Control and was advised to give him ice cream or an antacid. Three hours later in a follow-up call from Poison Control his mother said he had Maalox® and ice cream and this seemed to help. The following day his mother reported Poison Control that he was back to normal.

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References

Barceloux DG. Pepper and capsaicin (Capsicum and Piper species). Disease of the Month. 1990;55:380-390.

Fett DD. Capsicum peppers. Cutis. 2003;72:21-23.

Kim-Katz SY, Anderson IB, Kearney TE, MacDougall C, Hudmon KS, Blanc PD. Topical antacid therapy for capsaicin-induced dermal pain: a poison center telephone-directed study. Am J Emerg Med. 2010;28:596-602.

Williams SR, Clark RF, Dunford JV. Contact dermatitis associated with capsaicin: Hunan hand syndrome. Ann Emerg Med. 1995;25:713-715.

Poisoned?

Call 1-800-222-1222 or

HELP ME online

Prevention Tips

  • Wear rubber, latex, or nitrile gloves when working with hot peppers.
  • Open the windows or use fresh air if preparing or cooking hot peppers.
  • Do NOT touch face or eyes after preparing hot peppers.
  • If you choose to carry pepper spray, store and use it safely.

This Really Happened

Case 1: A young woman called Poison Control complaining of pain and blistering on her skin after handling hot chili peppers with bare hands an hour before. She had already tried washing with water, milk, and vinegar and had taken ibuprofen. Poison Control recommended applying a liquid antacid to the skin. However, the patient couldn't tolerate the pain and went to an emergency room. In the emergency room her hands were wrapped in gauze soaked in antibiotic ointment. She was given a narcotic pain reliever. The following day in a follow-up call from Poison Control the patient reported that her skin was somewhat improved but that her hands were still red, dry and cracked. She was using a moisturizing cream on the affected areas. Five days later she reported to Poison Control that she was much better.

Case 2: A teenage boy ate some food that had very hot chili peppers in it. He vomited and developed diarrhea and throat irritation. His mother called Poison Control and was advised to give him ice cream or an antacid. Three hours later in a follow-up call from Poison Control his mother said he had Maalox® and ice cream and this seemed to help. The following day his mother reported Poison Control that he was back to normal.

Capsaicin: When the "Chili" Is Too Hot (2024)

FAQs

What is the response of capsaicin? ›

Capsaicin, released as a fine spray when you bite into foods that contain it, triggers heat receptors in the skin, tricking the nervous system into thinking you're overheating. In response, your brain cranks up all of your body's cooling mechanisms. In short, you don't taste spicy food.

Does capsaicin break down with heat? ›

Cook or grill the peppers.

This study showed that capsaicin breaks down at around 400°F. Another study confirmed that heat, especially at higher temperatures paired with acidic conditions (lemon/lime juice, with tomatoes, etc.) reduced capsaicinoid concentrations.

How do you neutralize hot peppers in chili? ›

Serve the Chile Dish With Cream, Cheese, or Lime Juice

Acidic ingredients also neutralize capsaicin's burn somewhat, so squeezing some fresh lime juice on a spicy food can help a bit.

How do you make something less spicy? ›

6 Quick Ways to Tone Down a Dish That's Too Spicy
  1. Add more ingredients to dilute the spiciness. The easiest way to tone down a dish that's too spicy is to add more ingredients to lessen the proportion of the spicy element. ...
  2. Add dairy. ...
  3. Add acid. ...
  4. Add a sweetener. ...
  5. Add nut butter. ...
  6. Serve with bland, starchy foods.

What breaks down capsaicin? ›

The fat and oil in dairy products will dissolve the capsaicin and get rid of the burn. Opt for whole milk or full-fat sour cream or yogurt to do the trick. “It works just like soap dissolving grease particles when cleaning dishes,” Gulgas says. “Milk will dissolve and remove capsaicin from the reactive area.”

What completely neutralizes capsaicin? ›

Our Best Bet: Milk or Sweets

For example, milk is commonly used to soothe the tongue from the burning sensation caused by capsaicinoids because of its fat content. Other possible palate cleansers include beer, chocolate, sour cream, and sugar water, or other foods and beverages that contain calcium.

What reduces capsaicin? ›

Peanut, almond, or cashew butter are all rich in fat and can help dissolve capsaicin and mitigate some of the heat from chiles. If you're hesitant to add fat, you can also dilute the heat of a curry or stew by adding more water.

Does chili get less spicy as it cooks? ›

Most chillies lose their spiciness when cooked and mixed with other ingredients like dairy, acid, sugar, etc. But if that is still hot, chillies can be deseeded and soaked in water and vinegar to neutralise the capsaicin for a couple of hours before using it.

What makes capsaicin burn worse? ›

Capsaicin is a hydrophobic molecule, thanks to its hydrocarbon tail, so if you reach for a glass of ice-cold water, you're not going to wash any capsaicin away. In fact, you'll end up distributing it around your mouth, making the pain even worse.

Why is my chili not spicy? ›

Over caring for your peppers through excessive amounts of water and fertilizer will cause the peppers to be over sized and the capsicum in the membranes to become diluted, thus resulting is a milder tasting pepper.

What to eat or drink after eating a hot pepper? ›

Balancing it with an acid can help neutralize the capsaicin. This means that drinking or eating something acidic can give you some temporary relief from the burning sensations. Things such as lemonade or orange juice are great options. You can also try a tomato-based item.

Does lemon juice help with spicy food? ›

A squeeze of lemon or lime juice or a little vinegar can help cut through spiciness. Acidic foods tone down the spiciness in foods and can add some flavor, making this a good trick for seafood dishes or creamy soups and chowders.

Does vinegar reduce the heat in hot peppers? ›

Vinegar works because it is acidic, and other acidic foods—like tomatoes, lemons, or limes—can help calm the fire from a chile pepper, particularly if the tomatoes are not themselves infused with chiles in a salsa or other spicy application.

How much baking soda to neutralize chili? ›

Baking soda will neutralize the acid rather than mask it. Use 1/4 tsp for every serving in the pot, sprinkle it evenly around the top of the batch, and then stir it in well, once the bubbles have stopped it's ready for serving.

Should you add sugar to chili? ›

The chili tastes completely different without the brown sugar so if you like a subtle sweetness in your chili then you've just got to go for it! Trust me, it will not make your chili taste like candy. It's all about balance between spicy, smoky, and sweet.

Does sugar help spicy food? ›

Both honey and granulated sugar are effective in neutralizing a fiery mouth. Combining sugar with dairy can be very effective - think ice cream or flan. Lime juice, tomato juice or lemon juice can help relieve the burning sensation, which is why many recipes made with peppers incorporate an acidic component.

References

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